Recent Progresses on Inhibition of Bacterial Biofilms by Resveratrol: A Systematic Review Covering a Ten-Year Period

Abstract

The trans-isomer of resveratrol is a naturally occurring bioactive compound, and it is important because of its biological properties, which are beneficial to health. In recent years, interest in the antimicrobial activity of this molecule has grown; little is known, however, about its antibiofilm activity. This systematic review focused on the advances in research on the topic, in the decade up to 2021. With most studies coming from Asia, research on trans-resveratrol, alone or associated, have shown potential for exploration by the food industry. Low concentrations of the compound exhibit activity against biofilm formation by pathogenic bacteria whose inhibition mechanisms are multifactorial and involve quorum sensing. Few bacterial species, however, have been investigated up to now.